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Eskandari S E, Memariani M, Memariani H, Mohebali M, Khamesipour A. Molecular Diagnosis of Human Cutaneous Leishmaniasis and Identification of the Causative Leishmania Species in Iran: A Narrative Review. IBJ 2024; 28 (4) :148-155
URL: http://ibj.pasteur.ac.ir/article-1-4239-en.html

Molecular Diagnosis of Human Cutaneous Leishmaniasis and Identification of the Causative Leishmania Species in Iran: A Narrative Review

Seyed Ebrahim Eskandari ^*

Abstract:

Cutaneous leishmaniasis (CL) is a common form of leishmaniasis in underdeveloped countries. Although CL tends to be self-limiting, it can cause significant scars and may progress to more severe manifestations. Additionally, Leishmania species vary in susceptibility to the available treatments. The selection of treatment and clinical outcome of CL depend on the accurate determination of the Leishmania species. This mini-review aims to provide an overview of the molecular diagnosis techniques such as PCR-based assays, nucleic acid sequence-based amplification, and loop-mediated isothermal amplification utilized in the identification of Leishmania species in Iran.

Keywords: Humans, Iran, Leishmaniasis, Molecular diagnostic techniques

Full-Text [PDF 1166 kb]

Type of Study: Review Article | Subject: Molecular Microbiology

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