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Biomedical Journal
Volume 30, Issue 2 (Supplementary 2026)
IBJ 2026, 30(2): 32-32 |
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Sane Hoghough A, Nilforoushzadeh M A, Khani M, Amirkhani M A, Shokri B, Bozorg Savoji P, et al . Immediate Effect of Plasma Spark Technology on Wrinkles. IBJ 2026; 30 (2) :32-32
URL: http://ibj.pasteur.ac.ir/article-1-5535-en.html
URL: http://ibj.pasteur.ac.ir/article-1-5535-en.html
Aida Sane Hoghough * 
, Mohammad Ali Nilforoushzadeh , Mohammadreza Khani , Mohammad Amir Amirkhani , Babak Shokri , Pantea Bozorg Savoji , Erfan Ghasemi , Alireza Jafarzadeh , Alireza Dasdar
, Mohammad Ali Nilforoushzadeh , Mohammadreza Khani , Mohammad Amir Amirkhani , Babak Shokri , Pantea Bozorg Savoji , Erfan Ghasemi , Alireza Jafarzadeh , Alireza Dasdar
Abstract:
Introduction: Since the 2000s, researchers have studied the biological effects of reactive oxygen and nitrogen species generated by plasma on fibroblasts and collagen, particularly using plasma jet or Dielectric Barrier Discharge [1,2]. This research aimed to examine the effects of applying a plasma spark to reduce facial wrinkles.
Materials and Methods: A plasma spark device, manufactured by Plsma Fanavar Jam Company, was used for the treatment, and images were captured with a Visio face camera. Skin moisture, elasticity, and thickness of skin were measured using sonography and a multi-probe adaptor system. Patients signed an informed consent form, and their photographs were taken before applying a topical anesthetic oinment. After 30 minutes, the treatment was performed on the lateral canthal and naolabial lines using a dotting technique, along the length of the wrinkles. Post-treatment photographs and measurments were repeated immediately and at two-week intervals for a total of three follow-up sessions.
Results and Discussion: Plasma treatment reduced the thickness of the eyelid and nasolabial lines, measuring 20.81% and 22.29%, respectively. Additionally, changes in density were noted at 43.94% for eyelids and 35.6% for nasolabial lines, as measured by sonography. Colorimetry results showed improvements of 4.5% and 15.9% for both regions. These findings suggest that reactive oxygen species and heat have interacted with and influenced fibroblasts and collagen.
Conclusion: This study indicates that plasma treatment can help reduce wrinkles and improve skin smoothness over time, although an inflammatory response was observed immediately post-treatment.
Materials and Methods: A plasma spark device, manufactured by Plsma Fanavar Jam Company, was used for the treatment, and images were captured with a Visio face camera. Skin moisture, elasticity, and thickness of skin were measured using sonography and a multi-probe adaptor system. Patients signed an informed consent form, and their photographs were taken before applying a topical anesthetic oinment. After 30 minutes, the treatment was performed on the lateral canthal and naolabial lines using a dotting technique, along the length of the wrinkles. Post-treatment photographs and measurments were repeated immediately and at two-week intervals for a total of three follow-up sessions.
Results and Discussion: Plasma treatment reduced the thickness of the eyelid and nasolabial lines, measuring 20.81% and 22.29%, respectively. Additionally, changes in density were noted at 43.94% for eyelids and 35.6% for nasolabial lines, as measured by sonography. Colorimetry results showed improvements of 4.5% and 15.9% for both regions. These findings suggest that reactive oxygen species and heat have interacted with and influenced fibroblasts and collagen.
Conclusion: This study indicates that plasma treatment can help reduce wrinkles and improve skin smoothness over time, although an inflammatory response was observed immediately post-treatment.
Type of Study: Congress |
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