Iranian
Biomedical Journal
Volume 30, Issue 2 (Supplementary 2026)
IBJ 2026, 30(2): 32-32 |
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Sane Hoghough A, Nilforoushzadeh M A, Khani M, Amirkhani M A, Shokri B, Bozorg Savoji P, et al . Immediate Effect of Plasma Spark Technology on Wrinkles. IBJ 2026; 30 (2) :32-32
URL: http://ibj.pasteur.ac.ir/article-1-5535-en.html
URL: http://ibj.pasteur.ac.ir/article-1-5535-en.html
Aida Sane Hoghough * 
, Mohammad Ali Nilforoushzadeh , Mohammadreza Khani , Mohammad Amir Amirkhani , Babak Shokri , Pantea Bozorg Savoji , Erfan Ghasemi , Alireza Jafarzadeh , Alireza Dasdar1
, Mohammad Ali Nilforoushzadeh , Mohammadreza Khani , Mohammad Amir Amirkhani , Babak Shokri , Pantea Bozorg Savoji , Erfan Ghasemi , Alireza Jafarzadeh , Alireza Dasdar1
Abstract:
Introduction: Since the 2000s, researchers have studied the biological effects of reactive oxygen and nitrogen species generated by plasma on fibroblasts and collagen, particularly using jets or dielectric barrier discharge. This research aimed to examine the effects of applying plasma spark to reduce facial wrinkles.
Materials and Methods: A plasma spark device manufactured by Plasma Fanavar Jam was used for the treatment, and images were captured with a Visio face camera. Skin moisture, elasticity, and thickness were measured by sonography and a multi-probe adaptor system. Patients signed an informed consent form, and their photographs were taken before applying a topical anesthetic oinment. After 30 minutes, the treatment was performed on the lateral canthal and nasolabial lines using a dotting technique alon the length of the wrinkles. Post-treatment photographs and measurements were repeated immediately and subsequently at two-week intervals for a total of three follow-up sessions.
Results and Discussion: Plasma treatment reduced the thickness of the eyelid and nasolabial lines (20.81% and 22.29%) and density (43.94% and 35.6%), respectively, as measured by sonography. Colorimetry results showed improvements of 4.5% and 15.9% for both regions. These findings suggest that plasma reactive species and heat have interacted with and influenced fibroblasts and collagen.
Conclusion: Our study indicates that plasma treatment can be useful in reducing wrinkles and improving a skin smoothness over time, although an inflammatory response was observed immediately post-treatment.
Materials and Methods: A plasma spark device manufactured by Plasma Fanavar Jam was used for the treatment, and images were captured with a Visio face camera. Skin moisture, elasticity, and thickness were measured by sonography and a multi-probe adaptor system. Patients signed an informed consent form, and their photographs were taken before applying a topical anesthetic oinment. After 30 minutes, the treatment was performed on the lateral canthal and nasolabial lines using a dotting technique alon the length of the wrinkles. Post-treatment photographs and measurements were repeated immediately and subsequently at two-week intervals for a total of three follow-up sessions.
Results and Discussion: Plasma treatment reduced the thickness of the eyelid and nasolabial lines (20.81% and 22.29%) and density (43.94% and 35.6%), respectively, as measured by sonography. Colorimetry results showed improvements of 4.5% and 15.9% for both regions. These findings suggest that plasma reactive species and heat have interacted with and influenced fibroblasts and collagen.
Conclusion: Our study indicates that plasma treatment can be useful in reducing wrinkles and improving a skin smoothness over time, although an inflammatory response was observed immediately post-treatment.
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Type of Study: Congress |
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