Volume 2, Issue 3 And 4 (7-1998)                   ibj 1998, 2(3 And 4): 129-131 | Back to browse issues page

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Naghdi N, Goodwin N, Pocket S. Block of 5-HT2 Receptors Enhances Hippocampal Long-Term Potentiation. ibj. 1998; 2 (3 and 4) :129-131
URL: http://ibj.pasteur.ac.ir/article-1-865-en.html
The effect of endogenous serotonin on long-term potentiation (LTP) in region CAI was studied by blocking 5-HT2 receptors with ketanserin in rat hippocampal slices. Such a block significantly en-hanced long-term potentiation of the CAI population spike induced by high frequency stimulation of the schaffer collateral/ commissural pathway. This implies that serotonin acts on 5-HT2 receptors in CAI to repress long-term potentiation.
Type of Study: Full Length |

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