Iranian
Biomedical Journal
Volume 3, Issue 1 And 2 (1-1999)
IBJ 1999, 3(1 And 2): 53-57 |
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Poorheidari G. Isolation of a Postynaptic Blocker from the Venom of the Green Mamba, Dendroaspis angusticeps. IBJ 1999; 3 (1 and 2) :53-57
URL: http://ibj.pasteur.ac.ir/article-1-856-en.html
URL: http://ibj.pasteur.ac.ir/article-1-856-en.html
Abstract:
A blocker of postsynaptic acetylcholine receptors was isolated from venom of the Eastern green mamba Dendroaspis angusticeps, by gel filtration, ion-exchange and reverse phase high performance liquid chromatography. The isolated component blocks neuromuscular transmission and responses to exogenously applied acetylcholine in isolated chick biventer cervices preparations. These results suggest that postsynaptic blockers exist in venoms of all members of the Dendroaspis genus.
Type of Study: Full Length/Original Article |
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