Volume 4, Issue 1 (1-2000)                   ibj 2000, 4(1): 1-5 | Back to browse issues page

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Heidaran M A. Tissue Engineering: A Biological Solution for Tissue Damage, Loss or End Stage Organ Failure . ibj. 2000; 4 (1) :1-5
URL: http://ibj.pasteur.ac.ir/article-1-826-en.html

In recent years the science of tissue engineering has emerged as a powerful tool for the development of a novel set of tissue replacement parts and technologies. Recent advances in the fields of biomaterials, stem cell technologies, growth factor field and biomimetics have created a unique set of opportunities for investigators to fabricate lab-grown tissues from combination of extracellular matrices (scaffolds), cells, and bioactive molecules. Despite these breakthrough advances, the major challenges facing this new emerging field of bioengineering remain unresolved as lab-grown tissues still exhibit a general lack of functional and biomechanical stability needed for transplantation. A successful strategy to develop true human replacement parts requires a multidisciplinary approach that converges recent advances in tissue, matrix, growth factor and developmental biology with recent technological breakthroughs in tissueinformatics, bioinformatics, highthrouput combinatorial chemistry and stem cell technologies.

Type of Study: Review Article |

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