Iranian
Biomedical Journal
Volume 30, Issue 2 (Supplementary 2026)
IBJ 2026, 30(2): 5-5 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Aminjarrahi M, Sohbatzadeh* F, Mirzanejad S, brahimnezhad Darzi R, Rezanejad M. Pulsed Argon Arc Plasma Light as a New Tool for Efficient and Rapid Bacterial Inactivation. IBJ 2026; 30 (2) :5-5
URL: http://ibj.pasteur.ac.ir/article-1-5493-en.html
URL: http://ibj.pasteur.ac.ir/article-1-5493-en.html
Motahare Aminjarrahi * 
, Farshad Sohbatzadeh* , Saeed Mirzanejad , Reza Brahimnezhad Darzi , Mohammad Rezanejad
, Farshad Sohbatzadeh* , Saeed Mirzanejad , Reza Brahimnezhad Darzi , Mohammad Rezanejad
Abstract:
Introduction: Healthcare-associated infections pose a significant global threat. The limitations of conventional chemical disinfectants and continuous-wave UVC light have prompted the search for rapid, effective, and chemical-free alternative technologies. This study introduces a novel pulsed argon arc plasma light (PAAL) system as an efficient, rapid, and chemical-free alternative to conventional continuous-wave UVC germicidal lamps (GUV) for surface disinfection.
Materials and Methods: A lab-made PAAL system, utilizing argon gas at pressures of 40, 60, and 80 mbar and operating at 1 Hz, was fabricated. Its efficacy in inactivating Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923) was quantitatively evaluated and compared to a standard 15W GUV lamp. Bacterial colonies on agar plates were treated at a distance of 4 cm. The inactivation percentage was determined through digital image analysis after incubation. Additionally, optical emission spectra and UVC irradiance were characterized.
Results and Discussion: The PAAL system produced a broad optical spectrum with intense UVC emission lines. Increasing the argon pressure to 80 mbar significantly enhanced UVC irradiance, reaching 3195 µW/cm² at 254 nm—four times that of the GUV lamp (800 µW/cm²). For E. coli, the PAAL system achieved a 99.9% inactivation rate in 30 seconds (30 pulses), consuming only 1,677 Joules. In contrast, the GUV lamp required 900 seconds and 13,500 Joules to achieve a 99.6% inactivation rate. Similarly, the more resistant S. aureus, the PAAL system achieved 98.4% inactivation in 30 seconds, outperforming the GUV lamp (97.9% in 900 seconds). Statistical analysis confirmed the significance of pulse count and gas pressure.
Conclusion: The novel PAAL system demonstrates a paradigm shift in no-touch disinfection, offering superior speed, energy efficiency, and compactness compared to conventional GUV lamps. It holds exceptional promise for rapid decontamination cycles in clinical settings to combat healthcare-associated infections.
Materials and Methods: A lab-made PAAL system, utilizing argon gas at pressures of 40, 60, and 80 mbar and operating at 1 Hz, was fabricated. Its efficacy in inactivating Escherichia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923) was quantitatively evaluated and compared to a standard 15W GUV lamp. Bacterial colonies on agar plates were treated at a distance of 4 cm. The inactivation percentage was determined through digital image analysis after incubation. Additionally, optical emission spectra and UVC irradiance were characterized.
Results and Discussion: The PAAL system produced a broad optical spectrum with intense UVC emission lines. Increasing the argon pressure to 80 mbar significantly enhanced UVC irradiance, reaching 3195 µW/cm² at 254 nm—four times that of the GUV lamp (800 µW/cm²). For E. coli, the PAAL system achieved a 99.9% inactivation rate in 30 seconds (30 pulses), consuming only 1,677 Joules. In contrast, the GUV lamp required 900 seconds and 13,500 Joules to achieve a 99.6% inactivation rate. Similarly, the more resistant S. aureus, the PAAL system achieved 98.4% inactivation in 30 seconds, outperforming the GUV lamp (97.9% in 900 seconds). Statistical analysis confirmed the significance of pulse count and gas pressure.
Conclusion: The novel PAAL system demonstrates a paradigm shift in no-touch disinfection, offering superior speed, energy efficiency, and compactness compared to conventional GUV lamps. It holds exceptional promise for rapid decontamination cycles in clinical settings to combat healthcare-associated infections.
 |
Type of Study: Congress |
Subject:
Related Fields
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
IBJ is a member of Committee on Publication Ethics (COPE)
and follows its guidelines |
The articles of this journal are licensed under
a Creative Commons Attribution-NonDerivatives 4.0 International License. .png) |
 IBJ is owned and published by Pasteur Institute of Iran |