Global Perspectives on Rabies Prevention and Control: A Decade of World Rabies Day Themes and Progress toward Elimination (2016–2025)

Alamdary, Ashkan; Ajorloo, Mehdi; Gholami, Alireza

doi:10.61882/ibj.5398

Volume 30, Issue 3 And 2 (4-2026) IBJ 2026, 30(3 And 2): 125-131 | Back to browse issues page

‎ 10.61882/ibj.5398

PMID: 42454871

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Alamdary A, Ajorloo M, Gholami A. Global Perspectives on Rabies Prevention and Control: A Decade of World Rabies Day Themes and Progress toward Elimination (2016–2025). IBJ 2026; 30 (3 and 2) :125-131
URL: http://ibj.pasteur.ac.ir/article-1-5398-en.html

Global Perspectives on Rabies Prevention and Control: A Decade of World Rabies Day Themes and Progress toward Elimination (2016–2025)

Ashkan Alamdary

, Mehdi Ajorloo

, Alireza Gholami ^*

Abstract:

Rabies is a fatal zoonotic disease, responsible for approximately 59,000 human deaths annually; the majority occur in developing regions of Asia and Africa. This review explores worldwide efforts to prevent and control rabies during 2016–2025, using the evolving themes of World Rabies Day (WRD) as a framework. The research objective is to assess epidemiological trends, intervention strategies, challenges, and innovations related to the World Health Organization's target of zero human rabies deaths by 2030. The findings highlight a significant reduction in global rabies occurrence, with mass vaccination campaigns for dogs achieving 70% coverage in Guinea and a 95% decrease in human cases in Latin America. However, gaps in surveillance, vaccine shortages, and poor public education persist. Low-cost intradermal prophylaxis, monoclonal antibodies, and AI-driven surveillance systems are promising approaches but remain constrained by socioeconomic inequalities and insufficient investment. Achieving “Zero by 30” requires stronger collaboration, equitable resource distribution, and sustained community mobilization.

Keywords: One Health, Post-exposure prophylaxis, Rabies, Zoonoses

Full-Text [PDF 761 kb]

Type of Study: Perspective Review | Subject: Related Fields

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