Iranian
Biomedical Journal
Volume 27, Issue 2 And 3 (3-2023)
IBJ 2023, 27(2 And 3): 152-157 |
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Taherpoor A, Vojdani A, Hashemi S M A, Amali A, Mardani M R, Mobarhan M G, et al . Seroprevalence of Herpes Simplex Viruses Types 1 and 2 in a Population, Age 15-35 Years, of Mashhad City. IBJ 2023; 27 (2 and 3) :152-157
URL: http://ibj.pasteur.ac.ir/article-1-3828-en.html
URL: http://ibj.pasteur.ac.ir/article-1-3828-en.html
Ahmad Taherpoor 
, Arastoo Vojdani , Seyed Mohamad Ali Hashemi , Arian Amali , Mohammad Reza Mardani , Majid Ghayour Mobarhan , Habibollah Esmaily , MohammadTaghi Shakeri , Mansoureh Bakhshi , Mojtaba Meshkat , Amin Hooshyar Chechaklou , Samaneh Abolbashari * , Aida Gholoubi , Zahra Meshkat
, Arastoo Vojdani , Seyed Mohamad Ali Hashemi , Arian Amali , Mohammad Reza Mardani , Majid Ghayour Mobarhan , Habibollah Esmaily , MohammadTaghi Shakeri , Mansoureh Bakhshi , Mojtaba Meshkat , Amin Hooshyar Chechaklou , Samaneh Abolbashari * , Aida Gholoubi , Zahra Meshkat
Abstract:
Background: Considering the high prevalence and clinical importance of herpes simplex virus (HSV) infection worldwide, we aimed to evaluate the seroprevalence of HSV-1 and HSV-2 in a population aged between 15 and 35 years in Mashhad, Iran.
Methods: This cross-sectional study was conducted on 916 cases composed of 288 (31.4%) men and 628 (68.6%) women. Using ELISA method, the presence of IgM and IgG antibodies against HSV-1 and HSV-2 was assessed.
Results: Among the population studied, 681 (74.3%) cases were positive for anti-HSV antibodies, while 235 (25.7%) cases were negative. Moreover, no IgMs were found and all positive subjects had IgG antibodies. Age (p < 0.001), occupation (p < 0.001), education (p = 0.006), smoking (p = 0.029), and BMI (p = 0.004) demonstrated a significant association with HSV-1 and HSV-2 infection.
Conclusion: Our study indicates a high seroprevalence of HSV infection; however, there was no cases positive for IgM antibodies, suggesting the high prevalence of latent infection.
Methods: This cross-sectional study was conducted on 916 cases composed of 288 (31.4%) men and 628 (68.6%) women. Using ELISA method, the presence of IgM and IgG antibodies against HSV-1 and HSV-2 was assessed.
Results: Among the population studied, 681 (74.3%) cases were positive for anti-HSV antibodies, while 235 (25.7%) cases were negative. Moreover, no IgMs were found and all positive subjects had IgG antibodies. Age (p < 0.001), occupation (p < 0.001), education (p = 0.006), smoking (p = 0.029), and BMI (p = 0.004) demonstrated a significant association with HSV-1 and HSV-2 infection.
Conclusion: Our study indicates a high seroprevalence of HSV infection; however, there was no cases positive for IgM antibodies, suggesting the high prevalence of latent infection.
Type of Study: Short Communication |
Subject:
Molecular Microbiology
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