:: Volume 19, Issue 4 (10-2015) ::
ibj 2015, 19(4): 240-246 Back to browse issues page
Bacteria Etiological Agents Causing Lower Respiratory Tract Infections and Their Resistance Patterns
Salman Khan * , Singh Priti , Sachan Ankit

Background: Lower respiratory tract infections (LTRIs) are among the most common infectious diseases with potential life-threatening complications. Methods: The study consisted of 426 patients with suspected LTRIs from mid and far western region of Nepal between September 2011 and July 2014. The specimens were collected and processed according to the standard microbiological methods at the Central Laboratory of Microbiology of Nepalgunj Medical College, Nepal. Results: Among the isolated Gram-positive organisms, Streptococcus pneumonia (n = 30, 51.7%) was the most predominant pathogen, followed by Staphylococcus aureus (n = 28, 48.3%). Among the isolated Gram-negative organisms, Pseudomonas aeruginosa (n = 71, 35.32%) was the most predominant pathogen, followed by Haemophilus influenzae (n = 68, 33.83%), Klebsiella pneumonia (n = 36, 17.19%), and Escherichia coli (n = 26, 12.94%). The pattern of resistance varied regarding the bacteria species, and there were multi-resistant isolates. Also, a significant difference (P < 0.05) was observed between males and females for each type of bacterial species. Among 259 isolates, 86 (33.20%) were from children aged 1-10 years, which were statistically significant (P < 0.05) compared to the other age groups. Conclusions: P. aeruginosa and H. influenzae (Gram-negative) and S. pnemoniae (Gram-positive) were the most common bacterial isolates recovered from LTRIs. Age group of 1-10 years old was at a higher risk. Many isolates showed appreciable levels of antibiotic resistance due to antibiotic abuse. There is a need to increase surveillance and develop better strategies to curb the increasing prevalence of LRTI in this region of Nepal.

Keywords: Bacterial infections, Antimicrobial drug resistance, Respiratory system, Nepal
Full-Text [PDF 230 kb]      
Type of Study: Full Length | Subject: Related Fields
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Khan S, Priti S, Ankit S. Bacteria Etiological Agents Causing Lower Respiratory Tract Infections and Their Resistance Patterns. ibj. 2015; 19 (4) :240-246
URL: http://ibj.pasteur.ac.ir/article-1-1473-en.html

Volume 19, Issue 4 (10-2015) Back to browse issues page
Persian site map - English site map - Created in 0.18 seconds with 37 queries by YEKTAWEB 3781