Iranian Biomedical Journal
مجله بیومدیکال ایران
IBJ
Basic Sciences
http://ibj.pasteur.ac.ir
1
admin
1028-852X
2008-823X
-
10.61186/ibj
-
8888
-
en
jalali
1378
4
1
gregorian
1999
7
1
3
3
online
1
fulltext
en
Development of an ELISA Based Method for the Detection of Pemphigus vulgaris Autoantibodies
مقاله کامل
Full Length/Original Article
For the evaluation of autoantibodies in Pemphigus vulgaris (PV), an indirect ELISA assay was developed by using a semi-purified human epidermal skin extracted with approximately a molecular weight (M.W.) of 130-160 kDa. The evaluation of Pemphigus IgG, IgM and IgA autoantibodies in 75 patients and 50 control sera indicated that this indirect ELISA assay was a useful method for the detection of Pemphigus autoantibodies. Data of this study suggested that the mean OD (Optical Density) of specific IgG autoantibody was elevated in PV patients compared with the controls. The percentages of the total serum IgM and IgA antibodies were not statistically significant between patients and controls.
Pemphigus, Autoantibodies, ELISA
99
101
http://ibj.pasteur.ac.ir/browse.php?a_code=A-10-1-410&slc_lang=en&sid=1
Maryam
Ayatollahi
مریم
آیت اللهی
100319475328460057977
100319475328460057977
No
Zahra
Malek-Hosseini
زهرا
ملک حسینی
100319475328460057978
100319475328460057978
No
Mohammad-Taghi
Imani
محمد تقی
ایمانی
100319475328460057979
100319475328460057979
No
Sohaila
Joubeh
سهیلا
جوبه
100319475328460057980
100319475328460057980
No
Hossein
Mortazavi
حسین
مرتضوی
100319475328460057981
100319475328460057981
No
Abbas
Ghaderi
عباس
قادری
immunol@sums.ac.ir
100319475328460057982
100319475328460057982
Yes