en Study of the Heat-Treated Human Albumin Stabilization by Caprylate and Acetyltryptophanate مقاله کامل Full Length/Original Article <font face="times new roman,times,serif">Sodium salt of N-acetyl-DL-tryptophan (AT) and octanoic acid (caprylic acid CA) individually and in combination were studied as thermal stabilizer with different concentrations in heat treatment of human albumin solution. HPLC protein profiles before pasteurization of albumin showed less than 1% polymer. In free stabilizer albumin solution during pasteurization visible clot was formed. But by using variation of the above mentioned stabilizers, the amount of polymer was increased to about 4% during pasteurization (60&deg; C, 10 h). By increasing the heat to the visible clot formation point, the most effective stabilizer against visible clot formation was found to be CA. However, in drug formulation it is important to choose the variety and concentration of stabilizers in accordance with regulations.</font> Octanoate, Acetyltryptophanate, Albumin stabilizer 135 140 http://ibj.pasteur.ac.ir/browse.php?a_code=A-10-1-293&slc_lang=en&sid=1 Kamran Mousavi Hosseini کامران موسوی حسینی Yes Houri Rezvan حوری رضوان No Zabihollah Motalleb ذبیح ا... مطلبی No Sedigheh Chabokpey صدیقه چابک پی No Vida Mirbod ویدا میربد No