en زمان‌بندی دادنيلاسيون و تحليل mRNAهای مادری c-mos و cyclinA2 در طی مراحل اوليه جنين يک سلولی در موش ساير Others پژوهشي Research <font face="times new roman,times,serif">Early in the development of many animals, before transcription begins, any change in the pattern of protein synthesis is attributed to a change in the translational activity or stability of mRNA in the egg and early embryo. As a result, translational control is critical for a variety of developmental decisions, including oocyte maturation and initiation of preimplantation development. In this study, using real-time RT-PCR method, we defined the time course of degradation and deadenylation of an oocyte specific gene (c-mos) more precisely and a gene that is re-synthesized after ZGA (cyclin A2). Our data indicate that oocyte-specific transcript, c-mos, degrades rapidly while cyclin A2 mRNA does not and the deadenylation of c-mos mRNA precedes the process of degradation. Our findings suggest that time-dependent elimination of different maternal mRNA is a way for regulation of translation in early development of mouse embryos </font> Maternal mRNA, Mouse embryo, mRNA degradation, c-mos, Cyclin A2 Maternal mRNA, Mouse embryo, mRNA degradation, c-mos, Cyclin A2 179 183 http://ibj.pasteur.ac.ir/browse.php?a_code=A-10-1-224&amp;slc_lang=en&amp;sid=en Zohreh Alizadeh زهره عليزاده alizade_397@yahoo.com 10031947532846006119 Yes Parichehr Pasbakhsh پريچهر پاس بخش 10031947532846006120 No Aligholi Sobhani عليقلی صبحانی 10031947532846006121 No Mohammad Barbarestani محمد بربرستانی 10031947532846006122 No Marefat Ghafari معرفت غفاری 10031947532846006123 No Faride Etesam فريده اعتصام 10031947532846006124 No