Iranian Biomedical Journal
مجله بیومدیکال ایران
IBJ
Basic Sciences
http://ibj.pasteur.ac.ir
1
admin
1028-852X
2008-823X
-
10.61186/ibj
-
8888
-
en
jalali
1384
1
1
gregorian
2005
4
1
9
2
online
1
fulltext
en
تغییرات مشخصات حرکتی اسپرم موش در پاسخ به دوزهای مختلف پروژسترون در طول فرایندهای هایپراکیتویشن
Changes in Motility Parameters of Mouse Spermatozoa in Response to Different Doses of Progesterone during Course of Hyperactivation
مقاله کامل
Full Length/Original Article
<font face="times new roman,times,serif">The aim of this study was to evaluate changes that occur in motility parameters of progesterone treated mouse spermatozoa during course of hyperactivation. Mouse spermatozoa treated with different doses of progesterone were videotaped after 10 min and 90 min of incubation. For each sperm, one second of movement of the head-midpiece junction was traced from the videotape and for each tracing seven motility parameters were studied using computer assisted image analysis. For all progesterone treated spermatozoa, motility rate differed significantly from control group after 90 min of incubation. Motility parameters for high doses of progesterone 10 and 100 µg/ml showed hyperactivation occurred during 10 min of incubation. With treatment of 1 µg/ml progesterone, hyperactivated motility pattern of spermatozoa occurred 90 min after incubation similar to the control group showing that low dose of progesterone is unable to induce hyperactivation. In conclusion, progesterone induces hyperactivation in mouse sperm and reduces the motility rate during the time </font>
Progesterone, Hyperactivation, Spermatozoa, Mouse
73
79
http://ibj.pasteur.ac.ir/browse.php?a_code=A-10-1-210&slc_lang=en&sid=1
Majid
Katebi
مجید
کاتبی
katebi@sina.tums.ac.ir
100319475328460057439
100319475328460057439
Yes
Mansoureh
Movahedin
منصوره
موحدین
100319475328460057440
100319475328460057440
No
Mir Abbas
Abdolvahabi
میرعباس
عبدالوهابی
100319475328460057441
100319475328460057441
No
Mohammad
Akbari
محمد
اکبری
100319475328460057442
100319475328460057442
No
Farid
Abolhassani
فرید
ابوالحسنی
100319475328460057443
100319475328460057443
No
Aligholi
Sobhani
علیقلی
صبحانی
100319475328460057444
100319475328460057444
No
Fugaku
Aoki
Fugaku
Aoki
100319475328460057445
100319475328460057445
No