other <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="unicode-bidi:embed"><span style="line-height:115%"><strong><span style="line-height:115%"><span style="color:#0e101a">Introduction:</span></span></strong><span style="line-height:115%"> Many studies have explored the influence of allograft size and type, but their findings require clarification. This study aimed to conduct a comparative histological and histomorphometric evaluation of the effect of allograft type and particle size differences on bone regeneration in a rat model, an area that has not been addressed in previous research. </span></span></span><br> <span style="unicode-bidi:embed"><span style="line-height:115%"><b><span style="line-height:115%">Methods and Materials:</span></b><span style="line-height:115%"> Seventy male Wistar rats were randomly divided into seven groups: (1) no material, (2) 150&ndash;500 &micro;m of freeze-dried bone allograft (FDBA), (3) 150&ndash;1000 &micro;m of FDBA, (4) 1000&ndash;2000 &micro;m of FDBA, (5) allograft cancellous bone block, (6) putty form allograft, and (7) particulate autogenous bone. A full-thickness flap was created, and a 7-mm defect was prepared. After filling the defects, the rats were monitored in separate cages. Light microscopy histological evaluation was carried out in the eighth week. </span></span></span><br> <span style="unicode-bidi:embed"><span style="line-height:115%"><b><span style="line-height:115%">Results:</span></b><span style="line-height:115%"> Based on the findings, autogenous group exhibited the highest average in bone formation (<i>p</i> = 0.05). The FDBA (1000-2000 &micro;m and 150-1000 &micro;m) groups also displayed higher new bone formation averages than the other allograft groups (<i>p</i> = 0.05). The block and FDBA (1000-2000 &micro;m) groups had the highest residual bone average (<i>p</i> = 0.05). The control group demonstrated the highest connective tissue average (<i>p</i> = 0.05). </span></span></span><br> <b><span style="line-height:115%">Conclusion and Discussion:</span></b><span style="line-height:115%"> This study highlights the substantial impact of allograft type and particle size on bone regeneration. The autogenous bone graft consistently demonstrated the highest levels of new bone formation, indicating its superior performance within our experimental framework.</span><br> <br> <img alt="" src="./files/site1/images/888.jpg" style="width: 1000px; height: 36px;" ></span></span></div> Allografts, Bone regeneration, Dental implants 176 176 http://ibj.pasteur.ac.ir/browse.php?a_code=A-10-4696-183&slc_lang=other&sid=1 Niloufar Golafshan No Mohammad Mohammadi No Mohadeseh Arab Solghar No Mahsa Kalantari No Sina Kakooei No Sajjad Farrokhi Yes