other <div style="text-align: justify;"><span style="font-family:Times New Roman;"><span style="font-size:14px;"><span style="line-height:normal"><span style="unicode-bidi:embed"><b><span style="color:black">Introduction:</span></b> <span style="color:black">Parkinson&#39;s disease (PD) is a progressive neurological disorder that affects movement, balance, and speech. It is characterized by the gradual loss of dopamine-producing cells in the brain. While the Internet of Things (IoT) has immense potential, several challenges must be considered for the effective and safe use of this technology in this population. This review study examined IoT&#39;s challenges in PD patients.</span></span></span><br> <span style="line-height:normal"><span style="unicode-bidi:embed"><b><span style="color:black">Search Strategy:</span></b> <span style="color:black">In this study, scientific databases such as PubMed, Scopus, Web of Science, and Google Scholar were searched using the keywords &quot;Internet of Things,&quot; &quot;Parkinson&#39;s disease,&quot; and &quot;challenges.&quot; Inclusion criteria included original and non-original articles related to IoT in PD patients. Articles published between 2015 and 2024, full-text articles in English or Persian, and articles relevant to the topic were included. Irrelevant articles were excluded. Titles and abstracts of articles were then reviewed based on the inclusion criteria. The full texts of the published articles were also examined.</span></span></span><br> <span style="line-height:normal"><span style="unicode-bidi:embed"><b><span style="color:black">Results:</span></b><span style="color:black"> A total of 40 relevant articles were identified. The results indicated several challenges associated with using IoT for PD patient care, including privacy concerns. Collecting and sharing patient health data must be performed with caution to protect their privacy. However, IoT devices can gather vast amounts of personal information, which, if not adequately protected, could be vulnerable to misuse. Security is another significant concern; IoT devices can be susceptible to hacking and cyberattacks, potentially resulting in the theft of patient health information or even unauthorized control of the devices by hackers. Technological complexity poses additional challenges; some PD patients may struggle to use IoT devices and applications, especially those with limited computer skills. Cost is another factor; the installation, maintenance, and upgrading of IoT devices and applications can be expensive, creating a financial barrier for some patients and their caregivers. Finally, acceptance is an issue as some patients and caregivers may have reservations or resistance to incorporating IoT technology into healthcare.</span></span></span><br> <span style="line-height:normal"><span style="unicode-bidi:embed"><b><span style="color:black">Conclusion and Discussion:</span></b><span style="color:black"> While IoT has significant potential to enhance PD patient care, numerous challenges need to be addressed. Relevant stakeholders, including researchers, developers, healthcare providers, patients, and caregivers, must collaborate to develop and implement IoT solutions that are both beneficial and acceptable for PD patients.</span></span></span></span></span></div> <br> <span style="font-family:Times New Roman;"><img alt="" src="./files/site1/images/888.jpg" style="width: 1000px; height: 36px;" ></span> Internet of things, Nervous system diseases, Parkinson's disease 123 123 http://ibj.pasteur.ac.ir/browse.php?a_code=A-10-4696-127&slc_lang=other&sid=1 Negin Shahi No Mehraban Shahi Yes Nasrin Davaridolatabadi No Negar Shahi No