en Related Fields Related Fields مقاله مروری Review Article <em>Trichomonas vaginalis</em> is a flagellated parasite affecting about 276 million people annually worldwide. Tricomoniasis is associated with different complications in pregnant women and infants. 5&#39;-nitroimidazole derivatives (metronidazole, ornidazole, and tinidazole) are FDA approved drugs recommended for trichomoniasis treatment. Treatment with metronidazole 5&#39;-nitroimidazole derivatives is associated with many side effects, and drug resistance to metronidazole has been reported in some cases. Recently, many attempts have been made to evaluate the effects of plants on causative agents of vaginal infections. In our research, the national and international databases were searched and the effects of various herbal extracts on <em>T. vaginalis</em> in Iran were reviewed from 2006 to 2016. In articles investigated, some plants had favorable antitrichomonal effects and needed to be further investigated. All the plant extracts have only been evaluated <em>in vitro</em>. Surveys of different articles in this review show that the active ingredients present in different parts of plants, including aerial parts, leaves, flowers, stems, and root can be suitable sources for introducing and developing new antitrichomonal compounds. Trichomonas vaginalis, Medicinal plants, Iran, Herbal, Extract 285 293 http://ibj.pasteur.ac.ir/browse.php?a_code=A-10-1-682&slc_lang=en&sid=1 Zohreh Fakhrieh Kashan No Department of Medical Parasitology, School of Public Health , Tehran University of Medical Sciences, Tehran, Iran Mahdi Delavari Yes Department of Medical Parasitology, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran Mohsen Arbabi No Department of Medical Parasitology, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran Hossein Hooshyar No Department of Medical Parasitology, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran