fa Role of Epigenetics in Biology and Human Diseases Cancer Biology Cancer Biology مقاله مروری Review Article <p style="direction: ltr; ">For a long time, scientists have tried to describe disorders just by genetic or environmental factors. However, the role of epigenetics in human diseases has been considered from a half of century ago. In the last decade, this subject has attracted many interests, especially in complicated disorders such as behavior plasticity, memory, cancer, autoimmune disease, and addiction as well as neurodegenerative and psychological disorders. This<br> review first explains the history and classification of epigenetic modifications, and then the role of epigenetic in biology and connection between the epigenetics and environment are explained. Furthermore, the role<br> of epigenetics in human diseases is considered by focusing on some diseases with some complicated features,<br> and at the end, we have given the future perspective&nbsp;of this field. The present review article provides concepts with some examples to reveal a broad view of different aspects of epigenetics in biology and human diseases.</p> DNA modification, DNA methylation, Gene expression 246 258 http://ibj.pasteur.ac.ir/browse.php?a_code=A-10-1-620&slc_lang=fa&sid=1 Azam Moosavi No Ali Motevalizadeh Ardekani Ardekani@nigeb.ac.ir Yes