en Related Fields Related Fields مقاله کوتاه Short Communication <p style="direction: ltr; "><strong>Background</strong>: Retroviruses of human T-lymphotropic viruses (HTLV-1 and HTLV-2) have been demonstrated to be endemic in the north-eastern region of Iran. This study aims to determine HTLV-1 and HTLV-2 prevalence among healthy individuals in Neyshabur City during 2010-2014. <strong>Methods:</strong> A total of 8054 blood samples were collected from healthy participants in Neyshabur, North-Eastern Iran. The blood samples were screened for the presence of specific antibodies against HTLV-1 and HTLV-2 by using ELISA according to the manufacturer&rsquo;s instructions. <strong>Results</strong><strong>:</strong> The overall seropositivity rate for HTLV-1 and HTLV-2 was found to be 6.55% (528 out of 8054) among participants. <strong>Conclusion: </strong>Both HTLV-1 and HTLV-2 were demonstrated to be at a high rate in healthy individuals. However, a smaller number of asymptomatic carriers were found in this study, as compared to those identified in previous investigations in the city.&nbsp;&nbsp;</p> Human T-lymphotropic viruse, Seroepidemiology, Enzyme-linked immunosorbent assay, Iran 57 60 http://ibj.pasteur.ac.ir/browse.php?a_code=A-10-1-596&slc_lang=en&sid=1 Mohammad Salehi No Medical Diagnostic Laboratory of Neyshabour, Center of Medical, Pathological and Genetic Diagnostic Services, Iranian Academic Center for Education, Culture and Research (ACECR), Mashhad Branch, Mashhad, Iran Seyyed Khalil Shokouhi Mostafavi No Department of Microbiology, Islamic Azad University, Tehran Medical Science Branch, Tehran, Iran Abdolmajid Ghasemian No Department of Microbiology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran Mahmoud Gholami No Department of Biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran Abdolrahim Kazemi-Vardanjani bacteriology94@gmail.com Yes Shahrekord University of Medical Sciences, Shahrek Mohammad Karim Rahimi No Department of Microbiology, Islamic Azad University, Tehran Medical Science Branch, Tehran, Iran