TY - JOUR JF - انستیتو-پاستور-ایران JO - IBJ VL - 21 IS - 5 PY - 2017 Y1 - 2017/9/01 TI - Therapeutic effects of Iranian herbal extracts against Trichomonas vaginalis TT - N2 - Trichomonas vaginalis is a flagellated parasite affecting about 276 million people annually worldwide. Tricomoniasis is associated with different complications in pregnant women and infants. 5'-nitroimidazole derivatives (metronidazole, ornidazole, and tinidazole) are FDA approved drugs recommended for trichomoniasis treatment. Treatment with metronidazole 5'-nitroimidazole derivatives is associated with many side effects, and drug resistance to metronidazole has been reported in some cases. Recently, many attempts have been made to evaluate the effects of plants on causative agents of vaginal infections. In our research, the national and international databases were searched and the effects of various herbal extracts on T. vaginalis in Iran were reviewed from 2006 to 2016. In articles investigated, some plants had favorable antitrichomonal effects and needed to be further investigated. All the plant extracts have only been evaluated in vitro. Surveys of different articles in this review show that the active ingredients present in different parts of plants, including aerial parts, leaves, flowers, stems, and root can be suitable sources for introducing and developing new antitrichomonal compounds. SP - 285 EP - 293 AU - Fakhrieh Kashan, Zohreh AU - Delavari, Mahdi AU - Arbabi, Mohsen AU - Hooshyar, Hossein AD - Department of Medical Parasitology, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran KW - Trichomonas vaginalis KW - Medicinal plants KW - Iran KW - Herbal KW - Extract UR - http://ibj.pasteur.ac.ir/article-1-2134-en.html DO - 10.18869/acadpub.ibj.21.5.285 ER -