Showing 2 results for Otitis Media
Fatemeh Najdi, Zahra Najdi, Fatemeh Mirshekali,
Volume 28, Issue 0 (12-2024)
Abstract
Introduction: Recurrent otitis media with effusion is a common condition in childhood. Various studies have demonstrated that in addition to hearing loss, otitis media can lead to significant complications, including central auditory processing disorders (CAPDs). CAPD refers to how the central nervous system processes auditory information. Given the high prevalence of recurrent otitis media in children and its impact on CAPD, along with its association with issues such as attention deficit and difficulties in reading and writing, we attempted to evaluate the effects of recurrent acute otitis media on CAPD in children.
Methods and Materials: Based on Cochrane systematic review principles and PRISMA guidelines, a comprehensive search was conducted using keywords "auditory cortex disorders", "Central auditory disease", "Central auditory pathway disorder", "central auditory processing disorder" AND "Otitis media" AND "children" in electronic databases such as PubMed, Scopus, and Web of Science until June 2024. Also, the Google Scholar search engine was used to review grey literature. Inclusion criteria were (1) original studies investigating the effect of otitis media in children suffering from CAPD and (2) English language articles. All review studies, interventional studies, commentary, and letters to editors were excluded. Two authors conducted screening and data extraction independently, and any discrepancies were resolved by consensus involving a third author. Cochrane risk of bias assessment (ROB 2) tool was used to evaluate the bias of studies.
Results: Among the 9,125 articles retrieved, 8,922 duplicates and irrelevant titles and abstracts were removed, leaving 203 articles that met the eligibility criteria, of which eight were included in the final analysis. Most studies were conducted in Asia, with a mean participant age of 7.6 years. All eight included studies demonstrated the negative impact of recurrent otitis media on auditory ability, particularly in children who experience recurrent otitis media in the first few months of life, a critical period for developing the auditory nervous system.
Conclusion and Discussion: One can influence the management of CAPD and the future direction of child research. It is recommended that greater emphasis be placed on studying otitis media during childhood.
Maedeh Rahimzadeh, Ebrahim Sabarifard, Ariana Pournasrariani, Maryam Dabirifard,
Volume 28, Issue 0 (12-2024)
Abstract
Introduction: Otitis media is the most common disorder that causes hearing loss in children. The leading cause of this disease is the formation of biofilms and microorganisms in the ear airways. Silver nanoparticles are key nanotechnology components with high antimicrobial and antioxidant activity, especially against Staphylococcus aureus. This study aimed to investigate the effect of silver nanoparticles in treating otitis media in children.
Methods and Materials: This study was conducted systematically in June 2024 by searching for the keywords middle ear, silver nanopractic, therapy, and children in the PUBMED, Science Direct, Scopus, and Google Scholar databases by removing duplicate and unrelated articles. Finally, 17 Persian and English articles published from 2017 to 2022 were reviewed and studied.
Results: Studies have shown that silver nanoparticles, such as gels, implants, and prostheses, have been used to treat middle ear infections. These particles have promising antimicrobial and antibiofilm properties against pathogens common in drug-resistant otitis media, including Streptococcus pneumoniae, Pseudomonas aeruginosa, Escherichia coli, and Aspergillus flavus. The clinical use of this nano-seed has a significant effect on improving patients' hearing. Silver particles stimulate cytoplasmic contractions and generate excitatory waves on the surface of the cell membrane. These contractions result in cell wall rupture and cell death. It also inhibits the expression of genes related to cell division and ultimately inhibits the growth of bacterial biofilms.
Conclusion and Discussion: Silver nanoparticles can be used in treatment-resistant middle ear infections. These particles are inexpensive and available because they can be extracted from garlic extract. It is suggested to use Tanshinone II. A to improve antibacterial function.
.png)
