Showing 3 results for Hospitalization
Fatemeh Bastan, Sepide Gharesheikhloo, Samaneh Hajy Molla Rabi, Nahid Abbasi Khoshsirat, Kiyarash Bakhshande,
Volume 28, Issue 0 (12-2024)
Abstract
Introduction: The incidence of generalized tonic-clonic seizures (GTCS) in patients with COVID-19 has been of growing concern. Understanding this characteristics and biomarker profiles of this population associated with GTCS is essential for improving patient management and outcomes. This study aimed to evaluate the incidence of GTCS in patients hospitalized with COVID-19 and identify key biomarkers associated with this neurological manifestation.
Methods and Materials: A retrospective analysis was conducted on patients admitted to the Iranian population between April and September 2021. The study included two groups: case, consisting of patients with COVID-19 and GTCS, including 40 participants, and control, comprising patients with COVID-19 but without GTCS, including 80 participants. Demographic data, seizure episodes, hospitalization duration, and key biomarkers, including SpO2, blood sugar, sodium, and calcium, were collected and analyzed.
Results: The results showed that there can be a significant relationship between previous seizure history and seizures due to COVID-19. Also, people with a history of cerebral vascular accidents experienced a higher rate of GTCS. Significant findings suggested that patients with COVID-19 and GTCS were younger and had a shorter hospitalization duration than those without GTCS. The variations in key biomarker values between the two groups indicated potential associations of SpO2, blood sugar, sodium, and calcium with the occurrence of GTCS in COVID-19 patients.
Conclusion and Discussion: Our findings enhance the understanding of the clinical characteristics and biomarker profiles associated with GTCS in patients with COVID-19.
Fateme Molaalinejad, Marzieh Mahmudimanesh, Ahmad Sadeghi, Fateme Eydi,
Volume 28, Issue 0 (12-2024)
Abstract
Introduction: Poisoning in childhood is a significant global issue and one of the most common reasons for visits to medical facilities. In addition, poisoning is a leading cause of death among children. Consequently, prioritizing children's health is a crucial indicator of overall societal health, necessitating further research in this area. This study aimed to investigate the epidemiology of poisoning in children admitted to Imam Khomeini Hospital in Esfarayen from 2018 to 2023.
Methods and Materials: In this cross-sectional study, the records of all individuals under 18 who referred to Imam Khomeini Hospital in Esfarayen between 2018 and 2023 were examined. Data were collected from archives of the hospital. The analysis was conducted using SPSS 26, and frequency and crosstab tables were used.
Results: The rate of poisoning in girls (59.9%) was higher than in boys (40.5%). Among 1,147 hospitalized children due to poisoning, 593 cases (51.7%) were older than 13 years, 84 cases (7.3%) were between 6 and 12 years old, and 470 cases (41%) were less than 5 years old. The most common cause of poisoning was drugs (54.8%), followed by opium (22.7%), methadone (5.4%), alcohol (4.4%), organophosphorus poison (3.4%), and detergents (9%). Other substances included tramadol (2.7%), carbon dioxide (0.9%), petroleum (0.8%), rat death poison (0.7%), amphetamine (0.6%), gasoline (4 0.0%), insecticide (0.3%), and poisonous plants (0.2%). Opium poisoning was the highest among children under five years of age (48.1%), and drug poisoning was the most prevalent poisoning in the age groups of 6 to 12 years (46.4%) and over 13 years (75.5%).
Conclusion and Discussion: Considering the high rate of drug poisoning, training on how to store drugs, drug sensitivities, as well as paying attention to family and psychological issues, especially for girls at puberty, seems necessary to prevent suicide. Also, considering the higher rate of opium poisoning in children under five years of age, welfare intervention to identify abused children or necessary counseling for families is very important.
Parisa Jalali, Abdolali Golpayegani,
Volume 28, Issue 0 (12-2024)
Abstract
Introduction: Considering the importance of the effectiveness of vaccination in reducing the severity of COVID-19 and mortality, knowledge of the effect of the vaccine on the severity of COVID-19 in communities is critical. Therefore, this study aimed to evaluate the effect of COVID-19 vaccines on the severity of COVID-19 in southeastern Iran (the Bam region).
Methods and Materials: A case-control study of a total of 2,082 adults aged 18 years was conducted to evaluate the associations between hospitalization due to COVID-19 and previous vaccination with existing vaccines (including Sinopharm, AstraZeneca and CovIran Barkat) in the country. Multinomial logistic regression was used, and relative risk (RR) and 95% confidence intervals (CIs) were calculated.
Results: After controlling for potential confounders, multinomial logistic regression revealed that COVID-19 vaccination reduced the likelihood of hospitalization for males and females in temporary wards (RRmen = 0.22 vs. RRwomen = 0.34), general wards (RRmen = 0.25 vs. RRwomen = 0.31), and intensive care units (RRmen = 0.47 vs. RRwomen = 0.77), with a p value of 0.001. The RR of hospitalization in all wards decreased for men and women who received Sinopharm or AstraZeneca and for women who received the Barkat vaccine. However, only a significant difference was detected in the reduction in patients who received the Sinopharm vaccine (p = 0.001).
Conclusion and Discussion: The findings show that vaccination is related to reducing the severity of the disease in the hospital. Therefore, increasing the vaccinated population can reduce the severity of COVID-19 and the need for intensive care in hospitals.
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