Showing 2 results for Salehi-Abargouei
Shayesteh Fazilat, Bahareh Sasanfar, Amin Salehi-Abargouei,
Volume 28, Issue 0 (Supplementary 2024)
Abstract
Introduction: Cardiovascular diseases (CVD) account for approximately one-third of all deaths. Diet is one of the most important factors affecting healthy life expectancy, as it is related to the onset of CVD and various chronic diseases related to lifestyle. Most current evidence suggests that dairy products have a neutral or positive effect on human CVD. Specific types of dairy products may have varying associations with atherosclerotic CVD. Research has shown a positive association between high-fat milk consumption and an increased risk of coronary heart disease. The findings in this area could benefit from greater consistency. Therefore, this study aimed to explore the relationship between dairy intake and coronary artery stenosis.
Methods and Materials: This cross-sectional study recruited 720 patients (aged 35-75 years) who met the inclusion criteria and were referred for angiography between July 2020 and November 2021 to Afshar Hospital, a central heart disease hospital in Yazd City, Iran. To assess the presence and intensity of coronary artery disease, we used the Gensini and Syntax scores. Data on general information, dietary food, and other variables were gathered by trained interviewers using specific questionnaires. Dietary intake was evaluated by a validated 178-item semi-quantitative food frequency questionnaire that has been applied for the past year. High-fat dairy products include high-fat milk, strained yogurt, cream cheese, ice cream, curd, and dough. Low-fat dairy products include low-fat milk, low-fat yogurt, and chocolate milk. Logistic regression was used in crude and adjusted models to investigate the relationship between dairy consumption and coronary artery stenosis.
Results: There were no significant associations between low-fat dairy intake and the odds of Gensini and SYNTAX scores for the upper versus lower tertile among the entire population in both the crude and adjusted models. Also, for high-fat dairy intake, there was no significant association between the odds of genuine and syntax scores for the upper versus lower tertile among the entire population in both the crude and adjusted model. In subgroup analyses by BMI, neither low-fat nor high-fat dairy intake was associated with an increased likelihood of coronary artery stenosis for the upper versus lower tertile in the crude and adjusted model.
Conclusion and Discussion: The present study found no significant association between high and low-fat dairy intake and the odds of coronary artery stenosis. Prospective studies are needed for more investigation.

Narges Fatehi-Firouzabadi, Bahareh Sasanfar, Amin Salehi-Abargouei,
Volume 28, Issue 0 (Supplementary 2024)
Abstract
Introduction: Non-communicable diseases, particularly cardiovascular diseases (CVDs), significantly contribute to global mortality and negatively impact the quality of life of young people and adults. Unhealthy diets are one of the most important modifiable risk factors for CVDs. Grains like wheat and rice are dietary staples in Iran. While whole grains are beneficial and can play a key role in a healthy diet, research on their association with CVD compared to refined grains is limited. Therefore, in this study, we aimed to evaluate the association between whole and refined grain consumption and compare their roles in developing CVD, specifically coronary artery disease (CAD).
Methods and Materials: This cross-sectional study was conducted among 720 patients undergoing coronary angiography at Afshar Hospital, a referral hospital in Yazd, Iran. The convenience method was used for sampling. The coronary artery stenosis was assessed using Gensini (GS) and SYNTAX scores (SS). Dietary intake was assessed using a validated 178-item Food Frequency Questionnaire (FFQ). Corn on bread, wheat flour, corn, barley, and bulgur were classified as whole-grain sources. In contrast, various pieces of bread (Lavash, barbecue, Sangak, Taftoon, baguette, and toast), rice, spaghetti, biscuits, digestive biscuits, vermicelli, and Reshte were considered refined grain sources. Multi-variable adjusted logistic regression was used to obtain odds ratios for coronary artery stenosis severity across whole grain and refined grain tertiles. The analyses were first adjusted for age, energy, and sex in the first model and additionally for marriage, menopausal status, physical activity, economic status, job, educational level, smoking, drug addiction, Diabetes, and body mass index (BMI) in model 2. Subgroup analysis based on BMI was also performed. Statistical data analysis was performed using STATA software version 14.
Results: No significant association was found between whole grain intake and GS or SS in the crude and fully adjusted model. Additionally, there was no significant association between refined grain intake and GS or SS in the crude and fully adjusted models. After subgroup analyses based on BMI, these associations remained non-significant.
Conclusion and Discussion: The findings of this study show a nonsignificant association between whole grain or refined grain consumption and CAD. Further prospective studies are crucial to investigate this association in more detail.
