Iranian
Biomedical Journal
Volume 11, Issue 1 (1-2007)
IBJ 2007, 11(1): 59-63 |
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Kaya S, Sesli Cetin E, Cicioglu Aridogan B, Onal S, Demirci M. Distribution of Hepatitis B Virus (HBV) Genotypes among HBV Carriers in Isparta. IBJ 2007; 11 (1) :59-63
URL: http://ibj.pasteur.ac.ir/article-1-456-en.html
URL: http://ibj.pasteur.ac.ir/article-1-456-en.html
Abstract:
The aim of this study was to investigate the prevalence of hepatitis B virus (HBV) genotypes in Isparta, Southwest of Turkey, as well as the clinical features and transmission route for patients with HBV infections. Methods: Patients (n = 135) with HBV infection were included in the study. Epidemiological and clinical data were obtained. HBV genotypes were determined with a preS2 epitope ELISA kit. Results: Although the HBV transmission route remained unidentified in 51.1% of the patients, blood contact was determined as the most common probable transmission route (38.5%). One hundred twenty-four (91.8%) of 135 samples, could be genotyped. One hundred fifteen (85.1%) were genotyped as type D/E, six (4.4%) were genotyped as type A, two (1.4%) were genotyped as type C, and one (0.7%) were genotyped as type F. Conclusion: Genotype D/E is determined as the predominant HBV genotype circulating in Isparta, Southwest of Turkey. No relationship between genotypes and disease severity and transmission route has been detected.
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