Volume 25, Issue 4 (7-2021)                   IBJ 2021, 25(4): 308-309 | Back to browse issues page


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Tabibzadeh A, Esghaei M, Zamani F, Soltani S, Yousefi P, Karbalaie Niya M H. ORF8 ∆382 Mutation: A Possible Viral Prognostic Biomarker for the Severity of the COVID-19. IBJ 2021; 25 (4) :308-309
URL: http://ibj.pasteur.ac.ir/article-1-3420-en.html
Abstract:  
To the editor:
Since the initial onset of the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic from Wuhan, China in December 2019, the virus is now spread all around the world, and the disease is named COVID-19. Based on the WHO report on April 18, 2021, there are now more than 140 million confirmed cases and three millions deaths due to this disease. The virus pathogenesis, clinical features, and therapeutic approaches have comprehensively been reviewed. In addition, it has been indicated that patients' medical background and the age factor are associated with the mortality rate. Regardless of the clinical presentations and the disease mortality, the mental effects of the current pandemic among medical staff and the general population are critically important, and the pandemic might trigger stress, anxiety, and depression........
Keywords: COVID19, Mutation, ORF8

References
1. Coronavirus disease (COVID-19) Weekly Epidemiological Update and Weekly Operational Update. Reterieved from: https://www.who.int/ emergencies/diseases/novel-coronavirus-2019/situation-reports.
2. Wiersinga WJ, Rhodes A, Cheng AC, Peacock SJ, Prescott HC. Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (COVID-19): a review. JAMA 2020; 324(8): 782-793. [DOI:10.1001/jama.2020.12839]
3. Torales J, O'Higgins M, Castaldelli-Maia JM, Ventriglio A. The outbreak of COVID-19 coronavirus and its impact on global mental health. International journal of social psychiatry 2020; 66(4): 317-320. [DOI:10.1177/0020764020915212]
4. Derry HM, Reid MC, Prigerson HG. Advanced cancer patients' understanding of prognostic information: Applying insights from psychological research. Cancer medicine 2019; 8(9): 4081-4088. [DOI:10.1002/cam4.2331]
5. White DB, Lo B. A framework for rationing ventilators and critical care beds during the COVID-19 pandemic. JAMA 2020; 323(18): 1773-1774. [DOI:10.1001/jama.2020.5046]
6. Su YC, Anderson DE, Young BE, Linster M, Zhu F, Jayakumar J, Zhuang Y, Kalimuddin S, Low JGH, Wah Tan C, Chia WN, Mak TM, Octavia S, Chavatte JM, Lee RTC, Pada S, Tan SY, Sun L, Yan GZ, Maurer-Stroh S, Mendenhall IH, Leo YS, Lye DC, Wang LF, Smith GJD. Discovery and genomic characterization of a 382-nucleotide deletion in ORF7b and ORF8 during the early evolution of SARS-CoV-2. MBio 2020; 11(4): e01610-e01620. [DOI:10.1128/mBio.01610-20]
7. Muth D, Corman VM, Roth H, Binger T, Dijkman R, Gottula LT, Gloz-Rausch F, Balboni A, Battilani M, Rihtarič D, Toplak I, Seage Ameneiros R, Pfeifer A, Thiel V, Drexler JF, Müller MA, Drosten C. Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission. Scientific reports 2018; 8(1): 15177. [DOI:10.1038/s41598-018-33487-8]
8. Young BE, Fong SW, Chan YH, Mak TM, Ang LW, Anderson DE, Lee CYP, Amrun SN, Lee B, Goh YS, Su YCF, Wei WE, Kalimuddin S, Chai LYA, Pada S, Tan SY, Sun L, Parthasarathy P, Chen YYC, Barkham T, Lin RTP, Maurer-Stroh S, Leo YS, Wang LF, Renia L, Lee VJ, Smith GJD, Lye DC, Ng LFP. Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study. The lancet 2020; 396(10251): 603-611. [DOI:10.1016/S0140-6736(20)31757-8]
9. Gong YN, Tsao KC, Hsiao MJ, Huang CG, Huang PN, Huang PW, Lee LM, Liu YC, Yang SL, Kuo RL, Chen KF, Liu YC, Huang SY, Huang HI, Liu MT, Yang JR, Chiu CH, Yang CT, Chen GW, Shih SR. SARS-CoV-2 genomic surveillance in Taiwan revealed novel ORF8-deletion mutant and clade possibly associated with infections in Middle East. Emerging microbes and infections 2020; 9(1): 1457-1466. [DOI:10.1080/22221751.2020.1782271]

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